I believe that everyone has heard about the application of ultrasound in medical applications, such as prenatal examination, breast screening, emergency trauma assessment, and treatment, such as oral periodontal treatment, extracorporeal shock wave lithotripsy, physical therapy. The reason why ultrasound is so popular in the medical community is that it does not involve radiation, so it is safer than X-ray inspection tools, small in size and cheaper, but you may not have thought that this ordinary sonic instrument can actually let The wound accelerates as fast as it turns.
Collaborated with scientists from the University of Sheffield and the University of Bristol, the Journal of Investigative Dermatology, a low-intensity ultrasound that stimulates wound cells and causes skin ulcers. The healing time of acne is accelerated by 30%.
Body healing mechanism
The mechanism of human wound healing is actually very complicated. Imagine that the wound is like a big hole in the ground, and the water pipe is broken and the water source is constantly flowing. The initial "coagulation period", blood cells and blood fibrin condense into blood clots, such as sandbags to block the wound; the second phase is "inflammation period", the injured cells will release histamine and other pro-inflammatory molecules, let the wound Vasodilatation and increased permeability, so liquids rich in white blood cells and serum proteins can penetrate into tissues to remove bacteria and necrotic substances. And afterwards, more white blood cells of different functions were added, and phagocytosis was eliminated by inflammatory cells, just like relays to eliminate the unhealthy wound healing.
Finally, entering the "proliferation phase", a variety of substances enter the wound area, such as fibroblast will produce fibrocytes, and produce collagen, which is like a scaffold in the wound, for reconstruction . The myofibroblast produces a gathering force that shrinks the wound, and by epithelialization, the epithelial cells cover the fibrous tissue layer by layer, gradually thickening, and the healing work is done.
For healthy people, it is hard to imagine how important it is to heal wounds, but in diabetes, smoking or elderly patients, poor peripheral blood circulation, poor white blood cell function, and reduced collagen synthesis all make the road to recovery. Hey, if you accidentally get chronic inflammation or even cause infection.
According to Dr. Mark Bass, Ph.D., director of the Research Center for Membrane Dynamics at the University of Sheffield, “About 25% of people with diabetes suffer from chronic ulcers, especially the feet, and the worst and most common end is amputation.â€
Faced with huge care needs and medical expenses, the most common method in today's medical community to fight chronic wounds is to “avoid infectionâ€, using antibiotics, plus debridement and special dressings to treat the patient's wound healing ability. Another method is to awaken cell repair by external factors, such as applying stem cells or extracted growth factors to the wound. However, this special treatment is expensive, and it is not affordable for the average person, and it is difficult to control the actual situation. The growth situation.
With the development of medical technology , is there no other innovative way to deal with difficult chronic wounds?
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