Smart insulin: new hope for diabetics

According to the BBC report, the National Academy of Sciences reported that scientists are full of hope for the "smart" insulin revolutionary diabetes control method being tested. With just one shot of smart insulin, you don't need to do blood tests and insulin to control your blood sugar all day long. Insulin can circulate in the body and activate when needed.

Tests on animals have shown that the technique is feasible, at least in rats, the test was successful. Scientists plan to turn to human trials soon. But experts warn that this technology needs to be tested for years after it is actually used for patient treatment. Patients with type 1 diabetes are either unable to secrete insulin or are unable to use their own insulin and need to rely on insulin to stay healthy.

If insulin is not injected, the patient's blood sugar will rise to a very dangerous level. However, insulin injection may also reduce blood sugar levels to very low, patients with type 1 diabetes must regularly check blood sugar to ensure that blood sugar levels are normal. Diabetes experts have been looking for ways to make blood sugar easier and more convenient, so "smart" insulin was born. There are many different types of smart insulin currently being developed, but all insulins are automatically activated when blood sugar is too high, and are turned off when blood sugar returns to normal.

Dr. Danny Chou of the Massachusetts Institute of Technology and his colleagues developed and tested a smart insulin in the lab. This is a common long-acting insulin with a modified chemical structure, with an additional set of molecules attached to the end that binds to proteins in the bloodstream, and when attached to the protein, the smart insulin is turned off. When blood sugar rises, the smart insulin turns on, and glucose locks the smart insulin, telling it to start working.

Dr. Zhou said: "My goal is to make life easier and safer for people with diabetes. This is an important advancement in insulin therapy." The International Juvenile Diabetes Research Foundation (JDRF) has been funding research on smart insulin. Karen Addington, JDRF's chief executive in the UK, said: "Many people with type 1 diabetes struggle to control their blood sugar every day. Smart insulin prevents hypoglycemia and controls blood sugar almost perfectly."

Dr. Richard Elliott of the British Diabetes Association said: "It takes years of research and clinical trials to understand whether similar drugs can be safely and effectively used in people with diabetes."

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