Cryogenic biology is closely related to many biological problems. Since the successful implementation of the theory in the 1980s, Thermo Fisher Scientific and biological sample researchers and guardians have worked hard in the field of cryobiology for many years. Today Enclose the things that relive the ultra-low temperature refrigerator.
The basic gold of cryogenic biology must be from 0 ° C to -135 ° C biological samples in different physical forms of water. When the temperature drops to -80 °C, the life activity in the biological sample is significantly reduced, and the water is also formed into hexagonal ice crystals into square ice crystals, and the damage is weakened. This is the theoretical basis for the ultra-low temperature refrigerator to store different kinds of biological samples in the short-term and short-term. .
Regardless of the factors before the sample is placed in the ultra-low temperature refrigerator and the cryoprotectant, for the ultra-low temperature refrigerator itself, for our researchers, how to calculate the reliable, what basis can be referenced?
Really suitable for the cooling capacity of biological samples
Most of the ultra-low temperature refrigerators use the principle of cascading refrigeration. In addition to the time from the room temperature to -86 °C, the temperature drop from -50 °C to -86 °C is actually more concerned. From the room temperature, we only start at the beginning. It can be used once at startup, but the temperature drop to -80 °C at -50 °C is more widely used in our daily use. The cooling rate of this period determines the safety of the samples we keep in it.
1-min door opening time
Store the sample in a cryogenic environment. The shorter the time above -60 °C, the better, but the baby always takes the sample? Thermo Fisher tells you, Mo tangled, observing the thermal insulation capacity of the ultra-low temperature refrigerator, the strength of the online indicator is the 1-min door opening temperature, that is, how long after the refrigerator is closed, it can return to a safe temperature (usually -75 ° C).
Assuming that warmed a time of ultra-low temperature freezer for an hour, count the number of samples in one day, it means that all samples throughout the day in an unstable state, it is clear that a small partner to 1-min is the time to open the door to warm faster, refrigeration The powerful refrigerator makes the sampling process more comfortable.
Insulation capacity
The temperature difference between the inside and outside of the low temperature refrigerator exceeds 100 °C. The good insulation design can reduce the loss of cold and temperature fluctuations, making the temperature of the cavity more stable and more energy efficient. The friends who play with the biological samples are most worried about the downtime caused by power outages. Here, another important performance indicator of the ultra-low temperature refrigerator is mentioned. No matter the load or full load, Thermo Fisher's refrigerator is generally higher than the similar brands on the market by more than 30% in this performance parameter. The no-load can reach more than 4 hours, and the full load is more than 10 hours.
Better experienceVacuum pressure balance
After the refrigerator is opened and closed, a part of the hot air enters the sealed cavity. After the hot air is cooled, the volume will be drastically reduced, causing a negative pressure inside, which will cause the refrigerator door to be unable to open again in a short time. The vacuum pressure balance port is equivalent to a pressure relief valve, which can well balance the pressure inside and outside the chamber and facilitate the quick opening of the refrigerator door.
Oversized condenser
The condenser is the key component of the heat dissipation of the refrigerator. The heat exchanged from the interior of the refrigerator is exchanged to the air through the condenser. The design of the condenser has a great influence on the refrigeration efficiency of the refrigerator. The condenser area of ​​Thermo Fisher's ultra-low temperature refrigerator is 15% larger than similar brands on the market, and the dual fan design improves the efficiency of cold and heat exchange and greatly improves the stability of the refrigerator.
*The article is from Thermo Fisher. If you have copyright issues, please contact Xiaobian within 30 days.
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