Release date: 2016-03-11
What did you first think of when you saw this title? Is "How to have a son"? If yes, please come back because I don't know how to have a son. Although I know that the sex of the fetus can be chosen through IVF technology, this is not allowed in our country after all.
If you really want to intervene in the gender of future generations, you can actually go to Thailand in the south, and it is allowed to choose sex in Thailand through IVF technology. Although you can choose the gender of the offspring in Thailand at will, if the child does not like it, it is very simple to change the gender in that magical country.
Although IVF technology can do this for a son, it is illegal in many countries, and the original intention of Robert G. Edwards, the father of IVF, is not the case. It is said that during Edwards' Ph.D. (1950s), he believed that in vitro fertilization (IVF, which we used to call IVF) might help in the treatment of infertility. Through more than two decades of systematic research, Edwards finally discovered the key principles of human fertilization, and he finally achieved the fertilization of egg cells in test tubes (ending to the source of today's "test tube baby").
"Father of IVF" by Robert G. Edwards [nobelprize.org]
On July 25, 1978, the world's first test-tube baby, Louise Brown, was born in the UK. Today, 5 million test-tube babies have been born worldwide. Edwards' technology benefits many families. It is Edwards' outstanding achievements in the field of human infertility treatment that earned him the 2010 Nobel Prize in Physiology or Medicine. On April 10, 2013, Edwards passed away at the age of 87.
The world's first test-tube baby Louise Brown was born [telegraph.co.uk]
As the number of IVFs increased, the academic community began to study this group. The researchers found that the infertile fertility progeny had the following problems compared with those who were born with normal fertilization: abortion, premature birth, low birth weight, and a higher risk of developing disease later in life.
The above four questions are gradually alleviating with the deepening of human understanding of themselves and the improvement of reproductive-related technologies. However, there is still a problem that has surfaced and made researchers wonder. It is the imbalance of the sex ratio of the baby. The researchers found that infants born through IVF technology were more likely to be male.
In fact, this phenomenon was discovered in the test tube breeding process of cattle and pigs as early as 1991 (this is probably because the animals are breeding fast and the market demand is large). In 2010, Australian scientists surveyed the sex ratio of test-tube babies in Australia and New Zealand and found that the ratio of test-tube baby to test-tube baby was 128:100 (1). Of course this is not caused by manual selection, because the Australian government is not allowed to do so. And some surveys show that many Australian couples go abroad to make IVF for their daughters. In 2014, a survey in the UK showed that the ratio of male to female IVF was 117:100 (2). The results of these two large surveys were higher than the natural male-female ratio of 105:100. Why is this happening?
With the proliferation of IVF groups, this problem has become increasingly prominent. Although it seems that the current population of 500,000 IVF and the annual growth rate of 350,000 are not enough to threaten the sex ratio of the global population. However, there is no way to guarantee that there will be any impact in the future. What's more, the researchers are still wondering if there is any secret behind us that we don't know. But the academic world has not had a clue in this field of research.
The research team from China Agricultural University on Monday unleashed the secret behind this phenomenon. The research by Tian Jianhui team of China Agricultural University in mice found that X chromosome inactivation (XCI) deficiency in in vitro fertilized embryos caused defects in female embryos and could not develop normally. Their research results are published in the Proceedings of the National Academy of Sciences (3).
Now everyone has a consensus that in the biosphere, we use XX for females and XY for males. During the development of a female embryo, one of the two Xs must be inactivated in order to complete the normal development of the female individual, which is called X chromosome inactivation. However, the Tian Jianhui team found that in the process of tube propagation, the female embryos had insufficient X chromosome inactivation, which led to the males of the offspring proliferated in the test tube significantly higher than the female individuals.
The Tian Jianhui team also found that the lack of X chromosome inactivation was caused by two related genes. Moreover, in the process of cultivation, if a chemical substance (vitamin A derivative) is added at the right time, the gender imbalance of the test mouse can be restored to a normal state.
From this point of view, the research of Tian Jianhui team not only explains the reasons for the gender imbalance of “test tube babyâ€, but also finds relevant solutions to the problem. In addition, their research also provides new insights into the common miscarriage, premature birth, and low birth weight of IVF.
Written here, in fact, this article is over. But I always felt that the end was a bit awkward. After all, it was only a long time before the slick tongue was pulled to the point. So in the end, here is a summary: the reason why IVF technology is more likely to give birth to a baby boy is because the baby embryo has an abnormality in the development process, resulting in the embryo not being able to develop normally, so the embryo implanted in the uterus is more likely to be a son.
Finally, I hope that the research results of Professor Tian’s team can be verified in humans as soon as possible, and contribute to the world’s leading assisted reproductive cause.
Source: Singularity Network
We're Professional Supplier Extract Powder manufacturers and suppliers in China specialized in providing high-quality products at low price. We warmly welcome you to buy or wholesale bulk Supplier Extract Powder for sale here from our factory. For a free sample, contact us now.
Supplier Extract Powder,Supplier Extract ,Supplier Powder Manufacturer in China
Shaanxi Kang New Pharmaceutical co., Ltd. , https://www.kangnewpharmas.com