The new development path of dry granulator under environmental pollution is imperative

The new development path of dry granulator under environmental pollution is imperative. The dry granulator work involves a wide range of national economic fields. It is not only an indispensable basic production link for a large number of industrial and agricultural products, but also a dry granulator. China's energy-consuming households account for about 12% of the total energy consumption of the national economy. In addition, the pollution caused by the dry granulator process is often an important source of environmental pollution in China. The improvement of dry granulator technology is closely related to the development of the entire national economy.

Faced with serious energy and environmental challenges, China Zui has recently adopted a comprehensive, coordinated and sustainable scientific development concept as the guiding ideology, and formulated a medium and long-term energy science and technology development strategy and development plan to 2020. This energy environment development strategy is formulated. It also pointed out the direction for the development of China's dry granulator technology, and it is imperative to explore the new development path of dry granulator technology. Compared with other control links in industrial and agricultural production, the task of energy saving and pollution prevention in the dry granulator process is particularly urgent.

First, dry granulators operate in a wide range of fields, and China's plastic granulation energy consumption accounts for almost half of the industry's energy consumption, reaching 12%.

Secondly, the pollution of the dry granulator to the environment is also rigorous. Among the various conventional dry granulators used by Zui Guang, more than three-quarters of them are hot air dry granulators. The dry granulator equipment is very polluting to the environment, for dry granulation. The transformation of the coal-fired furnace of the machine system has become an important issue to be solved urgently. The energy efficiency of the process of progressive dry granulators and the prevention of environmental pollution are complementary. By reducing the energy consumption of 100 million tons of standard coal, it can reduce emissions of CO2 and SO2 by more than 64 million tons in China, and its environmental benefits are very obvious.

Therefore, in exploring the new development path of dry granulator technology, it is necessary to comprehensively consider energy efficiency, environmental protection and product quality in order to achieve comprehensive, coordinated and sustainable development. To implement the development strategy of high-efficiency and green dry granulator, we must first take the resource-saving development road and become a combination and intelligent dry granulator. It is necessary not only to carry out fundamental transformation from the long process of the dry granulator, but also to carry out comprehensive and multi-level energy-saving technological transformation, and to develop dry granulator technology that applies renewable energy and industrial waste heat. From the government level, it is necessary to establish and improve the comprehensive evaluation criteria and industry standards for dry granulator equipment, establish macro-control and market regulation mechanisms, and accelerate the upgrading of dry granulator technology.

As the concept of quality from design (QualitybyDesign) continues to deepen, pharmaceutical production process development and pilot testing are increasingly valued by the pharmaceutical industry, aiming to solve the widespread use of pharmaceutical production processes from experimental amplification to mass production. The status quo of the problem.

Compared with the traditional wet granulation, the dry granulation has the granular material directly made to meet the user's requirements, without any intermediates and additives. After granulation, the product has uniform particle size and the bulk density is significantly increased, not only controlling pollution. It also reduces powder and energy costs, improves material appearance and fluidity, facilitates storage and transportation, and controls many advantages such as solubility, porosity and specific surface area. It is especially suitable for wet mixing granulation and one-step boiling granulation. materials.

Dry granulator use dry granulator is a new granulation method developed after the “one-step granulation” of the second generation granulation method. It is an environmentally friendly granulation process, which will directly A new device for pressing powder into granules. Dry granulators are widely used in granulation in the pharmaceutical, food, chemical and other industries. They are especially suitable for granulation of materials that are prone to decomposition or agglomeration when exposed to heat.

Dry granulation technology can be accomplished by a flat press granulator. The traditional Chinese medicine extract with a certain relative density is spray-dried to obtain a dry extract powder, and after adding certain auxiliary materials, it is pressed into a thin sheet by a dry extrusion granulator, and then pulverized into granules. The method requires less auxiliary materials, which is beneficial to improve the stability, disintegration and dispersibility of the particles. Generally dry extract powder plus 0.5-1 times auxiliary materials can be used. However, it should also be noted that the dry extract obtained by spray drying has strong wettability. Therefore, the key to the application of this method is to find suitable excipients. The excipients must have certain adhesive properties and are not easy to absorb moisture, such as lactose, pregelatinized starch, mannitol, water-soluble acrylic resin and cellulose derivatives. Wait. The material that is wet and easily decomposed or agglomerated is granulated. The granules made by the dry granulator can be directly compressed or filled into capsules.

The dry granules of the production type dry granulator are added from the top of the granulator and pre-pressed into the rolling machine. Under the double roll extrusion of the rolling mill, the material becomes a sheet, and the sheet becomes a sheet. The material is crushed, sized, sieved, etc. to obtain the desired granular product.

The material is mechanically compressed. Does not destroy the chemical properties of the material, and does not reduce the effective content of the product. The whole process is closed, no impurities flow in, the product purity is high, and there is no pollution to the environment. Automated production processes for large-scale production.

In addition to the dangerous goods that can cause explosion by extrusion friction, the unit can directly granulate most of the dry powder materials. The roll is water-cooled by a rotary joint, and the unit can also granulate the heat sensitive material.

Dry granulator features 1, vacuum automatic feeding, closed process automatic operation.

2. All parts in contact with the drug are quickly disassembled and cleaned separately.

3. The eccentric structure of the pressure wheel pair is monitored by the computer, so that the hardness and thickness of the sheet are evenly controllable.

4, double star wheel screen mesh, so that the fine powder is reduced to zui low.

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