Foodjx guide: freeze-dried products of biological products, need to have a certain physical form, uniform color, qualified residual moisture content, good solubility, high efficiency of survival, long shelf life, so not only the production process It is controlled by the sealed storage after lyophilization. More importantly, it is necessary to comprehensively control the parameters of each stage of the freeze-drying process in order to obtain high-quality products. The freeze-drying curve is the basic basis for the control of the freeze-drying process.
The freeze-drying curve is the curve relationship between the temperature and time of the freeze-dried box layer. Generally, the temperature is the ordinate and the time is the abscissa. It reflects the change of the plate temperature at different times during the freeze-drying process.
The freeze-drying curve is based on the sheet temperature. Because the product is controlled by the temperature of the layer, the temperature of the layer also controls the temperature of the product. To set the freeze-drying curve, the following factors need to be considered:
The product variety, the product has different eutectic points, the eutectic product requires low pre-freezing temperature, and the temperature of the laminating layer is also low when heating. It is necessary to find out the excellent freezing rate of a product according to the test to obtain high quality. Product and shorter freeze drying time.
Different time requirements for residual water are also different. Different requirements for different residual water requirements are different, and the freeze-drying time is also different. The amount of additional capacity, the type of the eliminator, the performance of the lyophilizer, etc. It is directly related to the formulation of the freeze-drying curve. Users should refer to the previous freeze-drying experience and set the freeze-drying curve according to the nature of the freeze-dried product in order to obtain high-quality freeze-dried products.
The freeze-drying curve is the curve relationship between the temperature and time of the freeze-dried box layer. Generally, the temperature is the ordinate and the time is the abscissa. It reflects the change of the plate temperature at different times during the freeze-drying process.
The freeze-drying curve is based on the sheet temperature. Because the product is controlled by the temperature of the layer, the temperature of the layer also controls the temperature of the product. To set the freeze-drying curve, the following factors need to be considered:
The product variety, the product has different eutectic points, the eutectic product requires low pre-freezing temperature, and the temperature of the laminating layer is also low when heating. It is necessary to find out the excellent freezing rate of a product according to the test to obtain high quality. Product and shorter freeze drying time.
Different time requirements for residual water are also different. Different requirements for different residual water requirements are different, and the freeze-drying time is also different. The amount of additional capacity, the type of the eliminator, the performance of the lyophilizer, etc. It is directly related to the formulation of the freeze-drying curve. Users should refer to the previous freeze-drying experience and set the freeze-drying curve according to the nature of the freeze-dried product in order to obtain high-quality freeze-dried products.
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