Release date: 2018-03-16
According to a report by the Asian News Channel of Singapore on March 13th, a collaborative study in Singapore has found a way to effectively culture pure liver cells from human stem cells, which may lead to a more effective treatment for liver failure.
The Singapore Genomics Institute (GIS), part of the Singapore Science and Technology Research Agency (A*STAR), announced on the 13th that it has successfully transplanted cultured hepatocytes through collaboration with the Institute of Molecular and Cell Biology (IMCB) and the Stanford University School of Medicine. In the mouse model, this increased the short-term survival of mice.
Dr. Ng Huck Hui, Executive Director of GIS, said: "In the process of waiting for a complete liver transplant in patients with liver failure, it is possible to culture a large number of stem cell-derived hepatocytes to maintain patient life, which improves patient survival and reduces liver. The burden of failure on society is of great significance."
According to reports, there are few treatments for liver disease, and it will bring huge medical and economic burdens. Currently, advanced liver failure can only be treated by liver transplantation, and more than 1 million patients worldwide die each year while waiting for a liver transplant.
A * STAR said that in order to solve this problem, the researchers' goal is to artificially culture a large number of liver cells from human embryonic stem cells.
Dr. Ange, a senior researcher at GIS, said: "Embryonic stem cells may become thousands of cell types in the human body. The key is to understand how to convert them into hepatocytes. These high-purity hepatocytes are cultured from embryonic stem cells. The use of these cells is an important step in cell transplantation. A major challenge for our team is to precisely control the process by which stem cells are transformed into hepatocytes."
Dr. Los, an associate professor at the Stanford University School of Medicine, said: "The key to our research is to identify six key nodes and map the path needed for stem cells to grow into hepatocytes."
Source: Bio Valley
Erythritol For Chocolate,Zerose Erythritol,Lakanto Erythritol,Pure Erythritol Powder
Ningxia Eppen Biotec CO.,LTD , https://www.nxeppen.com