[Pathogen] The pathogen is Listeria monocytogenes, Gram-positive, the morphology is flat or slightly curved microbacillus, more than a single presence or a 5-shaped or grid-like, sometimes chain-like or filamentous. The strain has no decidua, does not form spores, and can exercise. It is hemolyzed by type 3 on blood agar medium, and after 48 hours of culture, it can be stained for gram-negative and dark at both ends. The bacteria are more resistant to heat and can be killed within 30-40 minutes after 65C. Commonly used disinfectants are carbolic acid and alcohol for 2 minutes. Caustic soda and formalin can be killed within 3 minutes. The disease is sporadic and is sometimes endemic. Diseased animals and carriers are the source of the disease; rodents, especially the cryptic infections of rodents, wild animals, wild birds, etc., are often the natural reservoirs of the bacteria. The feces and secretions of these carriers contaminate feed and drinking water. With utensils, etc., they are transmitted to rabbits through the digestive tract, respiratory tract, eye conjunctiva, damaged skin and blood-sucking insects. Young rabbits are more susceptible than adult rabbits. [Symptoms] The incubation period of this disease is 2 days and can be divided into several types: acute (septic) type: common in young rabbits. It is generally depressed in spirit, refusal to eat, and the body temperature rises above 30C. The mucous membranes of the nasal cavity become inflamed and swollen. Nostrils exude serous and mucinous secretions and die after a few hours or three days. At the time of an acute necropsy, swelling of the neck and mesenteric lymph nodes was observed. Hydrothorax was accumulated in the thoracic cavity, pericardial sac, and abdominal cavity. Subcutaneous and pulmonary edema, and spleen and liver had slight pale yellow lesions. Subacute: Mainly manifested as metritis and meningitis. Rabbits with uterine inflammation, six days or a few days before delivery, appear lassitude, refuse to eat, quickly lose weight, dark red or tan liquid from the vagina, 5 days before delivery, suffering from abortion or death in rabbits; have abortion rehabilitation or Female rabbits that have absorbed fetal survival are infertile for long periods of time. Patients with meningitis often have dysfunction of the central nervous system, resulting in tremors, twisted necks, ring-shaped movements, loss of ability to eat and move, severely ill rabbits often appear "rolling" movements, ataxia, and gradual weight loss, after 10 days death. [pathological changes] rabbits with uterine inflammation can be seen thickening of the uterine wall, mucosal flushing, and sometimes visible Mummy degeneration of fetal or white curd mass; meningitis patients can see meningeal blood vessels filled with blood, brain and brain tissue congestion or edema. Chronic type: the course of the disease is milder, and there are more changes in mesolitis. Reddish-brown or purulent discharges from the vagina. Pregnant rabbits may have miscarriage or produce dry tires. Some diseased rabbits have meningitis changes, but the duration of the disease has been delayed to 12 months. [Diagnosis] 1. Rabbits with rhinitis, died quickly, rabbits have neurological symptoms and changes in metritis. 2. Meningeal congestion, edema, metritis, liver, spleen, heart necrosis. 3. Prenatal blood tests, mononuclear cells increased significantly, up to 1/2 of the total number of white blood cells. 4. Further diagnosis can be combined with bacteriological diagnosis: smear, culture and biochemical identification. [Prevention and Prevention] Rabbit farms should do a good job in daily health and epidemic prevention, exterminate rats, prevent rodents and other wild animals from entering rabbit farms, and do not introduce rabbits from infected areas. Since the disease can infect people and cause greater harm, once the diseased rabbit and suspicious rabbit are discovered, they should be immediately eliminated, buried or burned. China Agricultural Network Editor