Raw Antimalarial Quinine CAS 130-95-0

Model NO.: 130-95-0
Appearance: White Powder
Delivery Time: 4-7 Working Days
Shipping Time: Within 12 Hours
Shipping Ways: UPS, TNT, EMS, DHL, FedEx etc
Trademark: Desen Nutrition
Transport Package: Foil Bag
Specification: 10g/foil bag
Origin: China
HS Code: 2500666303
Model NO.: 130-95-0
Appearance: White Powder
Delivery Time: 4-7 Working Days
Shipping Time: Within 12 Hours
Shipping Ways: UPS, TNT, EMS, DHL, FedEx etc
Trademark: Desen Nutrition
Transport Package: Foil Bag
Specification: 10g/foil bag
Origin: China
HS Code: 2500666303
Quick Detail:

Product Name:Quinine
CAS:130-95-0
MF:C20H24N2O2
MW:324.42
EINECS:205-003-2
Product Categories:chiral;Alkaloids;Biochemistry;for Resolution of Acids;Inhibitors;Fluorescent;Quinoline
Mol File: 130-95-0.mol


Description:

Quinine, an alkaloid derived from the bark of the cinchona tree, is a blood schizontocidal agent that is more toxic than chloroquine.Quinine is used to treat malaria caused by Plasmodium falciparum. Plasmodium falciparum is a parasite that gets into the red blood cells in the body and causes malaria. Quinine works by killing the parasite or preventing it from growing. This medicine may be used alone or given together with one or more medicines for malaria.
Quinine should not be used to treat or prevent night time leg cramps. This medicine may cause very serious unwanted effects and should only be used for patients with malaria.It is administered parenterally to patients with severe or complicated malaria who cannot take drugs by mouth because of coma, convulsions or vomiting.
It is administered orally to less seriously ill patients with infections likely to be resistant to chloroquine or mefloquine, sometimes in combination with pyrimethamine/sulfadoxine or a tetracycline.
Quinine is an extremely basic compound and is, therefore, always presented as a salt. Various preparations exist, including the hydrochloride, dihydrochloride, sulphate, bisulphate, and gluconate salts; of these the dihydrochloride is the most widely used. Quinine has rapid schizonticidal action against intra-erythrocytic malaria parasites. It is also gametocytocidal for Plasmodium vivax and Plasmodium malariae, but not for Plasmodium falciparum. Quinine also has analgesic, but not antipyretic properties. The anti-malarial mechanism of action of quinine is unknown.

Uses:

Quinine is one of the oldest antimalarial drugs. At as early as the 15th century, the quinine-containing cinchona bark has been used extensively in the treatment of malaria with its antimalarial effect being similar to that of chloroquine that is through interfering with DNA synthesis effect. It is capable of inhibiting the erythrocytic stage of a variety of Plasmodium, being able to control the malaria symptoms. It also has certain killing effect on the gametes of vivax malaria and quartan malaria. However, it has no effect on the exoerythrocytic stage. Its major advantage is not easy to produce drug resistance, possibly due to that quinine binds the plasmodium DNA in a different way from chloroquine, so having no cross-resistance and can be used for the treatment of the infection of anti-chloroquine strains (especially Plasmodium falciparum). In addition, quinine can also exciting the uterus, inhibit the myocardium and have antipyretic analgesic effect. In addition to medicinal application, in analytical chemistry it can be used as the detection agent of bismuth, platinum and other metal ions and also be used for the separation agent of racemic organic acid.

Side effects:

1, cinchona reaction: this can occur when the daily quinine dosage exceeds more than 1g or a little longer, manifested as nausea, vomiting, tinnitus, headache, vision hearing loss, generally being able to be restored after drug withdrawal. 

2, specific reaction: it can be observed of acute hemolysis, dermatitis, itching, angioneurotic edema and bronchial asthma. A small number of patients with falciparum malaria, after administrating quinine, can get chills, fever, vomiting, hemoglobinuria, urinary retention and other acute hemolytic disease, called black urine heat which can be fatal in severe cases.

3, intravenous injection, can inhibit the heart and further cause decreased blood pressure and life-threatening shock, thus it is strictly prohibited to adopt intravenous injection. Intravenous infusion should be administrated with caution. Intramuscular injection is prone to cause tissue necrosis, and thus is generally not used except in cases that oral administration is not doable.


Our Delivery:

Raw Antimalarial Quinine CAS 130-95-0



Raw Antimalarial Quinine CAS 130-95-0

FAQ:

1)Location & Working Hours
We are an International source locate in China.
I will answer emails from Monday to Saturday, 8:30 am to 18:00 pm (GMT+8)

2)How long does it takes to get back a response from you?
You should receive a response in less than 24 hours.

3)How do I make an order?
When you choosed the products, please email me, and I will quote for you, if you are satisfied with it, then pay for it, the parcle will be sent for you as soon as possible.

4)How to track my order?
 After I ship your order and have the tracking number, you will receive an email notification. All tracking numbers I provide can be tracked at http://www.17track.net/en. Or you can ask me for helping you track it too.

5)How long does the whole process take, from making an order till receiving the package?
The package will be prepared within 1 working day after payment received and be sent out within 72 hours. 
The delivery time depends on the shipping situation and customs. 
The shipping time will not more than 15 working days at most.

6)How about  the shipping cost?
The shipping cost is for the whole order. No matter how many different items and quantity in one orders. The shipping cost will be charged only once.

7)Is there a minimum order?
For raw powder: MOQ is 10g
For oil liquid: MOQ is 50ml
For peptide vial: MOQ is 10 vials

8)Reship Policy
To U.S. We reship for free twice if your package gets seized. 
To other countries we reship for free once if your package gets seized. 
If you choose not to reship or the resent package failed to go through again, no refund will be made.

9)Payment Ways
We accept Bank Transfer(T/T ), Western Union, Moneygram, Bitcoin.
*** The Bitboin is a little special for us, our Bitcoin account is always changing, once I gave you the account number, please pay for it at once.  

10)Refund policy
Our company has a 2 reship policy all foreign countries in case of a seizure.
**We are not responsible if you throw away your products because you cannot find them in our disguised package. If you cannot find your products please email me and I will tell you where to find them.



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Quick Detail:

Product Name:Quinine
CAS:130-95-0
MF:C20H24N2O2
MW:324.42
EINECS:205-003-2
Product Categories:chiral;Alkaloids;Biochemistry;for Resolution of Acids;Inhibitors;Fluorescent;Quinoline
Mol File: 130-95-0.mol


Description:

Quinine, an alkaloid derived from the bark of the cinchona tree, is a blood schizontocidal agent that is more toxic than chloroquine.Quinine is used to treat malaria caused by Plasmodium falciparum. Plasmodium falciparum is a parasite that gets into the red blood cells in the body and causes malaria. Quinine works by killing the parasite or preventing it from growing. This medicine may be used alone or given together with one or more medicines for malaria.
Quinine should not be used to treat or prevent night time leg cramps. This medicine may cause very serious unwanted effects and should only be used for patients with malaria.It is administered parenterally to patients with severe or complicated malaria who cannot take drugs by mouth because of coma, convulsions or vomiting.
It is administered orally to less seriously ill patients with infections likely to be resistant to chloroquine or mefloquine, sometimes in combination with pyrimethamine/sulfadoxine or a tetracycline.
Quinine is an extremely basic compound and is, therefore, always presented as a salt. Various preparations exist, including the hydrochloride, dihydrochloride, sulphate, bisulphate, and gluconate salts; of these the dihydrochloride is the most widely used. Quinine has rapid schizonticidal action against intra-erythrocytic malaria parasites. It is also gametocytocidal for Plasmodium vivax and Plasmodium malariae, but not for Plasmodium falciparum. Quinine also has analgesic, but not antipyretic properties. The anti-malarial mechanism of action of quinine is unknown.

Uses:

Quinine is one of the oldest antimalarial drugs. At as early as the 15th century, the quinine-containing cinchona bark has been used extensively in the treatment of malaria with its antimalarial effect being similar to that of chloroquine that is through interfering with DNA synthesis effect. It is capable of inhibiting the erythrocytic stage of a variety of Plasmodium, being able to control the malaria symptoms. It also has certain killing effect on the gametes of vivax malaria and quartan malaria. However, it has no effect on the exoerythrocytic stage. Its major advantage is not easy to produce drug resistance, possibly due to that quinine binds the plasmodium DNA in a different way from chloroquine, so having no cross-resistance and can be used for the treatment of the infection of anti-chloroquine strains (especially Plasmodium falciparum). In addition, quinine can also exciting the uterus, inhibit the myocardium and have antipyretic analgesic effect. In addition to medicinal application, in analytical chemistry it can be used as the detection agent of bismuth, platinum and other metal ions and also be used for the separation agent of racemic organic acid.

Side effects:

1, cinchona reaction: this can occur when the daily quinine dosage exceeds more than 1g or a little longer, manifested as nausea, vomiting, tinnitus, headache, vision hearing loss, generally being able to be restored after drug withdrawal. 

2, specific reaction: it can be observed of acute hemolysis, dermatitis, itching, angioneurotic edema and bronchial asthma. A small number of patients with falciparum malaria, after administrating quinine, can get chills, fever, vomiting, hemoglobinuria, urinary retention and other acute hemolytic disease, called black urine heat which can be fatal in severe cases.

3, intravenous injection, can inhibit the heart and further cause decreased blood pressure and life-threatening shock, thus it is strictly prohibited to adopt intravenous injection. Intravenous infusion should be administrated with caution. Intramuscular injection is prone to cause tissue necrosis, and thus is generally not used except in cases that oral administration is not doable.


Our Delivery:

Raw Antimalarial Quinine CAS 130-95-0



Raw Antimalarial Quinine CAS 130-95-0

FAQ:

1)Location & Working Hours
We are an International source locate in China.
I will answer emails from Monday to Saturday, 8:30 am to 18:00 pm (GMT+8)

2)How long does it takes to get back a response from you?
You should receive a response in less than 24 hours.

3)How do I make an order?
When you choosed the products, please email me, and I will quote for you, if you are satisfied with it, then pay for it, the parcle will be sent for you as soon as possible.

4)How to track my order?
 After I ship your order and have the tracking number, you will receive an email notification. All tracking numbers I provide can be tracked at http://www.17track.net/en. Or you can ask me for helping you track it too.

5)How long does the whole process take, from making an order till receiving the package?
The package will be prepared within 1 working day after payment received and be sent out within 72 hours. 
The delivery time depends on the shipping situation and customs. 
The shipping time will not more than 15 working days at most.

6)How about  the shipping cost?
The shipping cost is for the whole order. No matter how many different items and quantity in one orders. The shipping cost will be charged only once.

7)Is there a minimum order?
For raw powder: MOQ is 10g
For oil liquid: MOQ is 50ml
For peptide vial: MOQ is 10 vials

8)Reship Policy
To U.S. We reship for free twice if your package gets seized. 
To other countries we reship for free once if your package gets seized. 
If you choose not to reship or the resent package failed to go through again, no refund will be made.

9)Payment Ways
We accept Bank Transfer(T/T ), Western Union, Moneygram, Bitcoin.
*** The Bitboin is a little special for us, our Bitcoin account is always changing, once I gave you the account number, please pay for it at once.  

10)Refund policy
Our company has a 2 reship policy all foreign countries in case of a seizure.
**We are not responsible if you throw away your products because you cannot find them in our disguised package. If you cannot find your products please email me and I will tell you where to find them.



More Hot Sale Products:
 
Product Name CAS NO.
Clobetasol Propionate 25122-46-7
Folic acid 59-30-3
Tranexamic Acid/Amstat 1197-18-8
Ribavirin  36791-04-5
Hydroxypropyl-Beta-Cyclodextrin 128446-35-5 
Chloral Hydrate 302-17-0 
Gentamycin Sulfate 1405-41-0
Levamisole HCl  16595-80-5
8-Hydroxyquinoline 148-24-3
Sulfamethoxazole 723-46-6 
Tetramisole Hydrochloride 5086-74-8 
Isotretinoin 4759-48-2
Quinine 130-95-0
Quinine dihydrochloride 130-89-2
Tenofovir Disoproxil Fumarate 202138-50-9
Caffeic Acid Phenethyl Ester 115610-29-2
Predni solone 50-24-8
Aminophylline  317-34-0
Albuterol Sulfate 51022-70-9
Aldactone  52-01-7
Tiletamine Hydrochloride 14176-50-2
Xylazine Hydrochloride  23076-35-9
Xylazine  7361-61-7 
Rebamipide 90098-04-7
Tretinoin 302-79-4
Food Additives

Food additives are substances added to food to preserve flavor or enhance taste, appearance, or other sensory qualities. AMULYN can provide many different kinds of food additives, including Natural Pigment, natural sweeteners, probiotic powders, etc. Among them, the most popular one is phycocyanin, which can be used in ice cream, cocktails, and baking to add color; Lutein can be used to protect eyesight and is mainly used in health products, such as capsules and oral liquids; probiotics are mainly used to regulate the balance of intestinal microorganisms and can be used in solid beverages, yogurt, etc.

Natural Pigment,Phycocyanin,Blue Spirulina Powder,Lutein,Probiotics Powder

Xi'an Gawen Biotechnology Co., Ltd , https://www.amextract.com