According to foreign media, scientists have developed a new method to repair defective genes in hematopoietic stem cells from patients with hereditary immunodeficiency disorders, X-linked chronic granulomatosis (X-CGD). Scientists transplanted repaired stem cells into mice, which develop into normal-functioning white blood cells, which proves that this method can be used to treat patients with X-CGD disease.
X-CGD is a hereditary disease with limited treatment options, caused by mutations in the CYBB gene, which cause NOX2 protein deficiency and impair leukocyte anti-infective ability. White blood cells in patients with X-CGD do not normally kill germs, so they are susceptible to infection and threaten their lives. In the latest study, scientists from the National Institute of Allergy and Infectious Diseases (NIAID) under the National Institutes of Health focused on CYBB mutations, in which a single change in the genetic code would result in the inactivation of NOX2 protein.
The researchers isolated hematopoietic stem cells from two patients and targeted and repaired the mutant gene using the gene editing technology CRISPR-Cas9. This targeted gene repair method can restore the defective CYBB gene sequence to normal human sequences, and it is difficult to distinguish between the corrected gene and the normal gene. In the process, the researchers did not detect any unexpected effects of the CRISPR-Cas9 gene editing technology. In contrast, other methods of restoring the function of a mutant gene often lead to additional changes, including the addition or loss of genetic material.
Fruit juice drinks is a beverage made of fruit juice products obtained by physical methods such as pressing, centrifugation and extraction. Fruit juice retains most of the nutrients in the fruit, such as vitamins, minerals, sugar and pectin in dietary fiber. Often drinking fruit juice can help digestion, moisten the intestines and supplement the lack of nutrients in the diet.
There are two kinds of fruit juice: pure fruit juice and compound fruit juice. As far as pure fruit juice is concerned, it can be divided into two types: one is to directly use the original juice, and the other is to dehydrate the freshly squeezed fruit juice first, and then add water to reduce it into concentrated fruit juice. Most pure fruit juices are concentrated. AGOLYN offers various flavors of honey tea, such as honey Citron tea etc.
Juice Drinks,Honey Tea,Honey Citron Tea,Goji Berry Juice
Xi'an Gawen Biotechnology Co., Ltd , https://www.seoagolyn.com